Fluxtrol | Modified Solenoid Coil That Efficiently Produces High Amplitude AC Magnetic Fields with Enhanced Uniformity for Biomedical Applications

Modified Solenoid Coil That Efficiently Produces High Amplitude AC Magnetic Fields with Enhanced Uniformity for Biomedical Applications

  • Authors:V. Nemkov, R. Ruffini, R. Goldstein, J. Jackowski, T. L. DeWeese, R. Ivkov
  • Abstract:This is a continuation of studies previously reported [1] with the primary focus of optimizing an inductor design. The potential benefits of hyperthermia for cancer therapy, particularly metastatic cancers of the prostate, may be realized by the use of targeted magnetic nanoparticles that are heated by alternating magnetic fields (AMF). To further explore the potential of this technology, a high-throughput cell culture treatment system is needed. The AMF requirements for this research present challenges to the design and manufacture of an induction system because a high flux density field at high frequency must be created in a relatively large volume. Additional challenges are presented by the requirement that the inductor must maintain an operating temperature between 35 °C and 39 °C with continuous duty operation for one hour or longer. Results of simulation and design of two devices for culture samples and for in-vitro tests of multiple samples in uniform field is described.
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